decreased immature B cell number_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>,Tg(IghMyc)22Bri/0

http://metadb.riken.jp/0008215B6CgDynll1tm11JhhCd79atm1CreRethTgIghMyc22BriCd79atm1creRethCd79aDynll1tm11JhhDynll1tm11JhhTgIghMyc22Bri0Dynll1tm11JhhCd79aTgIghMyc22BriCd79atm1creReth

decreased immature B cell number_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>,Tg(IghMyc)22Bri/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dynein light chain LC8-type 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861457
• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774
• transgene insertion 22, Ralph L Brinster
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448238

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>,Tg(IghMyc)22Bri/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dynll1<tm1.1Jhh>|Cd79a<+>|Tg(IghMyc)22Bri|Cd79a<tm1(cre)Reth>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Dynll1<tm1.1Jhh> Cd79a<tm1(Cre)Reth> Tg(IghMyc)22Bri

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased immature B cell number
  http://purl.obolibrary.org/obo/MP_0008215

文献

http://purl.org/net/cito/citesAsAuthority

• David M. Wong, et.al., The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell Lymphoma., Cell reports, 2016, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/26832406