David M. Wong, et.al., The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell Lymphoma., Cell reports, 2016, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/26832406

David M. Wong, et.al., The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell Lymphoma., Cell reports, 2016, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dynll1<tm1.1Jhh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5755433

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased immature B cell number_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0008215B6CgCd79atm1CreRethAtmintm11JhhAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aAtmintm11JhhCd79aCd79atm1creReth
• decreased lymphoma incidence_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0010268B6CgDynll1tm11JhhCd79atm1CreRethTgIghMyc22BriCd79atm1creRethCd79aDynll1tm11JhhDynll1tm11JhhTgIghMyc22Bri0Dynll1tm11JhhCd79aTgIghMyc22BriCd79atm1creReth
• no abnormal phenotype detected_Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>
  http://metadb.riken.jp/0002169C57BL6NTacDynll1tm11JhhDynll1tm11JhhDynll1tm11JhhDynll1tm11Jhh
• decreased mature B cell number_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>
  http://metadb.riken.jp/0008211B6CgDynll1tm11JhhCd79atm1CreRethCd79atm1creRethCd79aDynll1tm11JhhDynll1tm11JhhCd79aCd79atm1creRethDynll1tm11Jhh
• decreased immature B cell number_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0008215B6CgCd79atm1CreRethAtmintm11JhhTgIghMyc22BriAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aTgIghMyc22Bri0Cd79atm1creRethTgIghMyc22BriCd79aAtmintm11Jhh
• increased B cell apoptosis_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0008782B6CgCd79atm1CreRethAtmintm11JhhTgIghMyc22BriAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aTgIghMyc22Bri0Cd79atm1creRethTgIghMyc22BriCd79aAtmintm11Jhh
• decreased immature B cell number_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>
  http://metadb.riken.jp/0008215B6CgDynll1tm11JhhCd79atm1CreRethCd79atm1creRethCd79aDynll1tm11JhhDynll1tm11JhhCd79aCd79atm1creRethDynll1tm11Jhh
• abnormal B cell morphology_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>
  http://metadb.riken.jp/0004939B6CgDynll1tm11JhhCd79atm1CreRethCd79atm1creRethCd79aDynll1tm11JhhDynll1tm11JhhCd79aCd79atm1creRethDynll1tm11Jhh
• increased lymphoma incidence_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Bcl2l11<tm1.1Ast>/Bcl2l11<tm1.1Ast>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0012431B6CgBcl2l11tm11AstCd79atm1CreRethAtmintm11JhhTgIghMyc22BriAtmintm11JhhAtmintm11JhhBcl2l11tm11AstBcl2l11tm11AstCd79atm1creRethCd79aTgIghMyc22Bri0Atmintm11JhhCd79aTgIghMyc22BriCd79atm1creRethBcl2l11tm11Ast
• increased tumor latency_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0009828B6CgCd79atm1CreRethAtmintm11JhhTgIghMyc22BriAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aTgIghMyc22Bri0Cd79atm1creRethTgIghMyc22BriCd79aAtmintm11Jhh
• decreased IgG1 level_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0008495B6CgCd79atm1CreRethAtmintm11JhhAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aAtmintm11JhhCd79aCd79atm1creReth
• decreased B cell number_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0005017B6CgCd79atm1CreRethAtmintm11JhhAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aAtmintm11JhhCd79aCd79atm1creReth
• decreased B cell number_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0005017B6CgCd79atm1CreRethAtmintm11JhhTgIghMyc22BriAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aTgIghMyc22Bri0Cd79atm1creRethTgIghMyc22BriCd79aAtmintm11Jhh
• decreased immature B cell number_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0008215B6CgDynll1tm11JhhCd79atm1CreRethTgIghMyc22BriCd79atm1creRethCd79aDynll1tm11JhhDynll1tm11JhhTgIghMyc22Bri0Dynll1tm11JhhCd79aTgIghMyc22BriCd79atm1creReth
• decreased pre-B cell number_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dynll1<tm1.1Jhh>/Dynll1<tm1.1Jhh>
  http://metadb.riken.jp/0008209B6CgDynll1tm11JhhCd79atm1CreRethCd79atm1creRethCd79aDynll1tm11JhhDynll1tm11JhhCd79aCd79atm1creRethDynll1tm11Jhh
• altered tumor susceptibility_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Ighm<tm1(Bcl6)Rdf>/Ighm<+>,Tg(Fcer2a-cre)5Mbu/0
  http://metadb.riken.jp/0002166B6CgAtmintm11JhhIghmtm1Bcl6RdfTgFcer2acre5MbuAtmintm11JhhAtmintm11JhhIghmtm1Bcl6RdfIghmTgFcer2acre5Mbu0TgFcer2acre5MbuIghmIghmtm1Bcl6RdfAtmintm11Jhh
• increased B cell apoptosis_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0008782B6CgCd79atm1CreRethAtmintm11JhhAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aAtmintm11JhhCd79aCd79atm1creReth
• decreased lymphoma incidence_Atmin<tm1.1Jhh>/Atmin<tm1.1Jhh>,Cd79a<tm1(cre)Reth>/Cd79a<+>,Tg(IghMyc)22Bri/0
  http://metadb.riken.jp/0010268B6CgCd79atm1CreRethAtmintm11JhhTgIghMyc22BriAtmintm11JhhAtmintm11JhhCd79atm1creRethCd79aTgIghMyc22Bri0Cd79atm1creRethTgIghMyc22BriCd79aAtmintm11Jhh

class

http://purl.org/net/cito/citesAsAuthority

• Dynll1<tm1.1Jhh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5755433