abnormal B cell activation_Fas<lpr>/Fas<lpr>,Tlr7<tm1Flv>/Y

http://metadb.riken.jp/0008217I129S1SvC57BL6MRLMpFaslprFaslprTlr7tm1FlvYFaslprTlr7tm1Flv

abnormal B cell activation_Fas<lpr>/Fas<lpr>,Tlr7<tm1Flv>/Y

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fas (TNF receptor superfamily member 6)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95484
• toll-like receptor 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176882

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fas<lpr>/Fas<lpr>,Tlr7<tm1Flv>/Y

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fas<lpr>|Tlr7<tm1Flv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * MRL/Mp

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal B cell activation
  http://purl.obolibrary.org/obo/MP_0008217

文献

http://purl.org/net/cito/citesAsAuthority

• Sean R. Christensen, et.al., Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus., Immunity, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16973389