abnormal medium spiny neuron morphology_Shank3<tm5.1Gfng>/Shank3<tm5.1Gfng>,Tg(CAG-cre/Esr1*)1Lbe/0

http://metadb.riken.jp/0008462I129S1Sv129S1SvImJ129X1SvJC57BL6JShank3tm51GfngShank3tm51GfngTgCAGcreEsr11Lbe0Shank3tm51GfngTgCAGcreEsr11Lbe

abnormal medium spiny neuron morphology_Shank3<tm5.1Gfng>/Shank3<tm5.1Gfng>,Tg(CAG-cre/Esr1*)1Lbe/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SH3/ankyrin domain gene 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1930016
• transgene insertion 1, Corrinne Lobe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677721

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Shank3<tm5.1Gfng>/Shank3<tm5.1Gfng>,Tg(CAG-cre/Esr1*)1Lbe/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Shank3<tm5.1Gfng>|Tg(CAG-cre/Esr1*)1Lbe

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal medium spiny neuron morphology
  http://purl.obolibrary.org/obo/MP_0008462

文献

http://purl.org/net/cito/citesAsAuthority

• Yuan. Mei, et.al., Adult restoration of Shank3 expression rescues selective autistic-like phenotypes., Nature, 2016, 530
  http://rdf.ncbi.nlm.nih.gov/pubmed/26886798