decreased spleen germinal center size_Ezh2<tm1Tara>/Ezh2<tm1Tara>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

http://metadb.riken.jp/0008484I129P2OlaHsdEzh2tm1TaraEzh2tm1TaraIghg1tm1creCgnIghg1Ezh2tm1TaraIghg1Ighg1tm1creCgn

decreased spleen germinal center size_Ezh2<tm1Tara>/Ezh2<tm1Tara>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy constant gamma 1 (G1m marker)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96446
• enhancer of zeste 2 polycomb repressive complex 2 subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:107940

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ezh2<tm1Tara>/Ezh2<tm1Tara>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ezh2<tm1Tara>|Ighg1<+>|Ighg1<tm1(cre)Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased spleen germinal center size
  http://purl.obolibrary.org/obo/MP_0008484

文献

http://purl.org/net/cito/citesAsAuthority

• Wendy. Béguelin, et.al., EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation., Cancer cell, 2013, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/23680150