decreased IgG1 level_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>

http://metadb.riken.jp/0008495I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog

decreased IgG1 level_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy constant mu
  http://metadb.riken.jp/db/mgi_rdf/MGI:96448

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ighm<tm1.1(IGH-2)Cog>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgG1 level
  http://purl.obolibrary.org/obo/MP_0008495

文献

http://purl.org/net/cito/citesAsAuthority

• Sophie. Duchez, et.al., Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20133609