decreased IgG1 level_Il18<tm1Aki>/Il18<tm1Aki>,Tg(KRT14-CASP1)1Miz/0

http://metadb.riken.jp/0008495I129P2OlaHsdC57BL6Il18tm1AkiIl18tm1AkiTgKRT14CASP11Miz0TgKRT14CASP11MizIl18tm1Aki

decreased IgG1 level_Il18<tm1Aki>/Il18<tm1Aki>,Tg(KRT14-CASP1)1Miz/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 18
  http://metadb.riken.jp/db/mgi_rdf/MGI:107936
• transgene insertion 1, Hitoshi Mizutani
  http://metadb.riken.jp/db/mgi_rdf/MGI:3621155

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il18<tm1Aki>/Il18<tm1Aki>,Tg(KRT14-CASP1)1Miz/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT14-CASP1)1Miz|Il18<tm1Aki>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgG1 level
  http://purl.obolibrary.org/obo/MP_0008495

文献

http://purl.org/net/cito/citesAsAuthority

• Hiroshi. Konishi, et.al., IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/12151598