Hiroshi. Konishi, et.al., IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99

http://rdf.ncbi.nlm.nih.gov/pubmed/12151598

Hiroshi. Konishi, et.al., IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(KRT14-Il18)#Knak
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388817

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased IgE level_Stat6<tm1Aki>/Stat6<tm1Aki>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0002492I129P2OlaHsdC57BL6Stat6tm1AkiStat6tm1AkiTgKRT14CASP11Miz0Stat6tm1AkiTgKRT14CASP11Miz
• increased circulating interleukin-18 level_Stat6<tm1Aki>/Stat6<tm1Aki>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0008635I129P2OlaHsdC57BL6Stat6tm1AkiStat6tm1AkiTgKRT14CASP11Miz0Stat6tm1AkiTgKRT14CASP11Miz
• decreased IgG1 level_Stat6<tm1Aki>/Stat6<tm1Aki>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0008495I129P2OlaHsdC57BL6Stat6tm1AkiStat6tm1AkiTgKRT14CASP11Miz0Stat6tm1AkiTgKRT14CASP11Miz
• dermatitis_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0001194C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• decreased IgE level_Il18<tm1Aki>/Il18<tm1Aki>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0002492I129P2OlaHsdC57BL6Il18tm1AkiIl18tm1AkiTgKRT14CASP11Miz0TgKRT14CASP11MizIl18tm1Aki
• dermatitis_Stat6<tm1Aki>/Stat6<tm1Aki>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0001194I129P2OlaHsdC57BL6Stat6tm1AkiStat6tm1AkiTgKRT14CASP11Miz0Stat6tm1AkiTgKRT14CASP11Miz
• increased IgG1 level_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0008499IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• excessive scratching_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0001412C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• dermatitis_Il1a<tm1Yiw>/Il1a<tm1Yiw>,Il1b<tm1Yiw>/Il1b<tm1Yiw>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0001194I129S1Sv129X1SvJC57BL6Il1atm1YiwIl1atm1YiwIl1btm1YiwIl1btm1YiwTgKRT14CASP11Miz0TgKRT14CASP11MizIl1btm1YiwIl1atm1Yiw
• increased circulating interleukin-18 level_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0008635IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• increased neutrophil cell number_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0000219C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• decreased T cell number_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0005018C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• parakeratosis_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0003427IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• skin edema_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0001786IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• abnormal dermis papillary layer morphology_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0009545IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• increased IgG1 level_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0008499C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• abnormal T cell physiology_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0002444IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• increased IgE level_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0002497IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• abnormal T cell physiology_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0002444C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• skin lesions_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0001212IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• increased circulating interleukin-18 level_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0008635C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• decreased T cell number_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0005018IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• increased neutrophil cell number_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0000219IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• abnormal histamine physiology_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0002503C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• decreased IgG1 level_Il18<tm1Aki>/Il18<tm1Aki>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0008495I129P2OlaHsdC57BL6Il18tm1AkiIl18tm1AkiTgKRT14CASP11Miz0TgKRT14CASP11MizIl18tm1Aki
• abnormal histamine physiology_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0002503IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• dermatitis_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0001194IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• skin lesions_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0001212C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• increased IgE level_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0002497C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• excessive scratching_Stat6<tm1Aki>/Stat6<tm1Aki>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0001412I129P2OlaHsdC57BL6Stat6tm1AkiStat6tm1AkiTgKRT14CASP11Miz0Stat6tm1AkiTgKRT14CASP11Miz
• acanthosis_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0001874IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• acanthosis_Tg(KRT14-Il18)#Knak/0
  http://metadb.riken.jp/0001874C57BL6TgKRT14Il18KnakTgKRT14Il18Knak0TgKRT14Il18Knak
• excessive scratching_Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0001412IC57BL6TgKRT14CASP11Miz0TgKRT14CASP11Miz
• abnormal histamine physiology_Stat6<tm1Aki>/Stat6<tm1Aki>,Tg(KRT14-CASP1)1Miz/0
  http://metadb.riken.jp/0002503I129P2OlaHsdC57BL6Stat6tm1AkiStat6tm1AkiTgKRT14CASP11Miz0Stat6tm1AkiTgKRT14CASP11Miz

class

http://purl.org/net/cito/citesAsAuthority

• Tg(KRT14-Il18)#Knak
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388817