decreased IgG1 level_Cd79a<tm1(cre)Reth>/Cd79a<+>,Huwe1<tm1.1Mak>/Y,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0008495I129P2OlaHsdC57BL6SJLCd79atm1creRethCd79aHuwe1tm11MakYTrp53tm1BrnTrp53tm1BrnTrp53tm1BrnCd79aCd79atm1creRethHuwe1tm11Mak

decreased IgG1 level_Cd79a<tm1(cre)Reth>/Cd79a<+>,Huwe1<tm1.1Mak>/Y,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• HECT, UBA and WWE domain containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926884
• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd79a<tm1(cre)Reth>/Cd79a<+>,Huwe1<tm1.1Mak>/Y,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Cd79a<+>|Cd79a<tm1(cre)Reth>|Huwe1<tm1.1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgG1 level
  http://purl.obolibrary.org/obo/MP_0008495

文献

http://purl.org/net/cito/citesAsAuthority

• Zhenyue. Hao, et.al., The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis., The Journal of experimental medicine, 2012, 209
  http://rdf.ncbi.nlm.nih.gov/pubmed/22213803