decreased IgG2b level_Sppl2a<tm1Dgen>/Sppl2a<tm1Dgen>

http://metadb.riken.jp/0008497B6129P2Sppl2atm1DgenSppl2atm1DgenSppl2atm1DgenSppl2atm1Dgen

decreased IgG2b level_Sppl2a<tm1Dgen>/Sppl2a<tm1Dgen>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal peptide peptidase like 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913802

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sppl2a<tm1Dgen>/Sppl2a<tm1Dgen>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sppl2a<tm1Dgen>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129P2-Sppl2a<tm1Dgen>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgG2b level
  http://purl.obolibrary.org/obo/MP_0008497

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel R. Beisner, et.al., The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain., The Journal of experimental medicine, 2013, 210
  http://rdf.ncbi.nlm.nih.gov/pubmed/23267013