decreased IgG3 level_Sppl2a<chompB>/Sppl2a<chompB>

http://metadb.riken.jp/0008498IC57BL6Sppl2achompBSppl2achompBSppl2achompB

decreased IgG3 level_Sppl2a<chompB>/Sppl2a<chompB>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal peptide peptidase like 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913802

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sppl2a<chompB>/Sppl2a<chompB>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sppl2a<chompB>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgG3 level
  http://purl.obolibrary.org/obo/MP_0008498

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel R. Beisner, et.al., The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain., The Journal of experimental medicine, 2013, 210
  http://rdf.ncbi.nlm.nih.gov/pubmed/23267013