increased IgG2a level_Fas<lpr>/Fas<lpr>,Tlr9<tm1Aki>/Tlr9<tm1Aki>

http://metadb.riken.jp/0008500MRLCgTlr9tm1AkiFaslprFaslprFaslprTlr9tm1AkiTlr9tm1AkiFaslprTlr9tm1Aki

increased IgG2a level_Fas<lpr>/Fas<lpr>,Tlr9<tm1Aki>/Tlr9<tm1Aki>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fas (TNF receptor superfamily member 6)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95484
• toll-like receptor 9
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932389

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fas<lpr>/Fas<lpr>,Tlr9<tm1Aki>/Tlr9<tm1Aki>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fas<lpr>|Tlr9<tm1Aki>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• MRL.Cg-Tlr9<tm1Aki> Fas<lpr>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgG2a level
  http://purl.obolibrary.org/obo/MP_0008500

文献

http://purl.org/net/cito/citesAsAuthority

• Sean R. Christensen, et.al., Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus., Immunity, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16973389