increased circulating tumor necrosis factor level_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0

http://metadb.riken.jp/0008553I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv

increased circulating tumor necrosis factor level_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038
• transgene insertion 12, Richard A Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136409

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stat3<tm1Flv>|Tg(Tek-cre)12Flv

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating tumor necrosis factor level
  http://purl.obolibrary.org/obo/MP_0008553

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas. Welte, et.al., STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/12571365