Thomas. Welte, et.al., STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100

http://rdf.ncbi.nlm.nih.gov/pubmed/12571365

Thomas. Welte, et.al., STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stat3<tm1Flv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2451328

class

http://purl.org/net/cito/citesAsAuthority

• Stat3<tm1Flv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2451328

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating interferon-gamma level_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0008577I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• cecum inflammation_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0009481I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• ileum inflammation_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0009482I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• abnormal ileum morphology_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0002581I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• premature death_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0002083I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• increased circulating tumor necrosis factor level_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0008553I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• intestinal ulcer_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0000512I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• intestinal inflammation_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001858I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• increased leukocyte cell number_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0000218I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• decreased body weight_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001262I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• colitis_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0002816I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• abnormal inflammatory response_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001845I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• abnormal innate immunity_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0002419I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• granulomatous inflammation_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0002500I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• liver inflammation_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001860I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• abnormal enzyme/coenzyme activity_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0005584I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• abnormal cecum morphology_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0000494I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• decreased body size_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001265I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• abnormal T-helper 1 physiology_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0005465I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• abnormal colon morphology_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0000495I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• weakness_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0000746I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv
• abnormal intestine morphology_Stat3<tm1Flv>/Stat3<tm1Flv>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0000477I129C3HC57BL6Stat3tm1FlvStat3tm1FlvTgTekcre12Flv0Stat3tm1FlvTgTekcre12Flv