abnormal interferon-gamma secretion_Drosha<tm1Litt>/Drosha<tm1.1Litt>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0008559I129129P2OlaHsdC57BL6FVBNDroshatm1LittDroshatm11LittGtROSA26Sortm1creERTNatGtROSA26SorDroshatm1LittDroshatm11LittGtROSA26Sortm1creERTNatGtROSA26Sor

abnormal interferon-gamma secretion_Drosha<tm1Litt>/Drosha<tm1.1Litt>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• drosha, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261425

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Drosha<tm1Litt>/Drosha<tm1.1Litt>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Drosha<tm1Litt>|Drosha<tm1.1Litt>|Gt(ROSA)26Sor<tm1(cre/ERT)Nat>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal interferon-gamma secretion
  http://purl.obolibrary.org/obo/MP_0008559

文献

http://purl.org/net/cito/citesAsAuthority

• Mark M W. Chong, et.al., The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease., The Journal of experimental medicine, 2008, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/18725527