decreased interferon-beta secretion_Irf3<tm1Ttg>/Irf3<tm1Ttg>,Irf7<tm1Ttg>/Irf7<tm1Ttg>

http://metadb.riken.jp/0008565I129P2OlaHsd129SSvEvIrf3tm1TtgIrf3tm1TtgIrf7tm1TtgIrf7tm1TtgIrf3tm1TtgIrf7tm1Ttg

decreased interferon-beta secretion_Irf3<tm1Ttg>/Irf3<tm1Ttg>,Irf7<tm1Ttg>/Irf7<tm1Ttg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interferon regulatory factor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1859179
• interferon regulatory factor 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1859212

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irf3<tm1Ttg>/Irf3<tm1Ttg>,Irf7<tm1Ttg>/Irf7<tm1Ttg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irf3<tm1Ttg>|Irf7<tm1Ttg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/SvEv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interferon-beta secretion
  http://purl.obolibrary.org/obo/MP_0008565

文献

http://purl.org/net/cito/citesAsAuthority

• Vijay A K. Rathinam, et.al., The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses., Nature immunology, 2010, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/20351692