decreased interferon-gamma secretion_Lat<tm6(DTR)Mal>/Lat<tm6(DTR)Mal>

http://metadb.riken.jp/0008567I129S2SvPasC57BL6Lattm6DTRMalLattm6DTRMalLattm6DTRMal

decreased interferon-gamma secretion_Lat<tm6(DTR)Mal>/Lat<tm6(DTR)Mal>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• linker for activation of T cells
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342293

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lat<tm6(DTR)Mal>/Lat<tm6(DTR)Mal>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lat<tm6(DTR)Mal>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interferon-gamma secretion
  http://purl.obolibrary.org/obo/MP_0008567

文献

http://purl.org/net/cito/citesAsAuthority

• Michael. Mingueneau, et.al., Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor., Immunity, 2009, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/19682930