decreased circulating interleukin-6 level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008597IC57BL6CBAGbatm11PmisGbatm12PmisTgMx1cre1Cgn0TgMx1cre1CgnGbatm12PmisGbatm11Pmis

decreased circulating interleukin-6 level_Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• glucosidase, beta, acid
  http://metadb.riken.jp/db/mgi_rdf/MGI:95665

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gba<tm1.1Pmis>/Gba<tm1.2Pmis>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Gba<tm1.2Pmis>|Gba<tm1.1Pmis>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating interleukin-6 level
  http://purl.obolibrary.org/obo/MP_0008597

文献

http://purl.org/net/cito/citesAsAuthority

• Pramod K. Mistry, et.al., Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20962279