increased circulating interleukin-18 level_Dnase2a<tm1Osa>/Dnase2a<tm2Osa>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008635I129S1Sv129S2SvPas129X1SvJC57BL6CBADnase2atm1OsaDnase2atm2OsaTgMx1cre1Cgn0Dnase2atm1OsaDnase2atm2OsaTgMx1cre1Cgn

increased circulating interleukin-18 level_Dnase2a<tm1Osa>/Dnase2a<tm2Osa>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• deoxyribonuclease II alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1329019
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dnase2a<tm1Osa>/Dnase2a<tm2Osa>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dnase2a<tm1Osa>|Dnase2a<tm2Osa>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating interleukin-18 level
  http://purl.obolibrary.org/obo/MP_0008635

文献

http://purl.org/net/cito/citesAsAuthority

• Kohki. Kawane, et.al., Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages., Nature, 2006, 443
  http://rdf.ncbi.nlm.nih.gov/pubmed/17066036