increased circulating interleukin-1 beta level_Hmgb1<tm1.1Ttg>/Hmgb1<tm1.1Ttg>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0008641I129P2OlaHsdC57BL6DBAHmgb1tm11TtgHmgb1tm11TtgTgAlbcre21Mgn0TgAlbcre21MgnHmgb1tm11Ttg

increased circulating interleukin-1 beta level_Hmgb1<tm1.1Ttg>/Hmgb1<tm1.1Ttg>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• high mobility group box 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96113

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hmgb1<tm1.1Ttg>/Hmgb1<tm1.1Ttg>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Hmgb1<tm1.1Ttg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating interleukin-1 beta level
  http://purl.obolibrary.org/obo/MP_0008641

文献

http://purl.org/net/cito/citesAsAuthority

• Hideyuki. Yanai, et.al., Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/24302768