increased interleukin-1 beta secretion_Apc<tm2.1Cip>/Apc<+>,Atg7<tm1Tchi>/Atg7<tm1Tchi>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0008657I129P2OlaHsdC57BL6C57BL6NCrljCBAJNCrljDBA2Apctm21CipApcAtg7tm1TchiAtg7tm1TchiTgVilcreERT223Syr0Atg7tm1TchiTgVilcreERT223SyrApctm21CipApc

increased interleukin-1 beta secretion_Apc<tm2.1Cip>/Apc<+>,Atg7<tm1Tchi>/Atg7<tm1Tchi>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• autophagy related 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921494
• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm2.1Cip>/Apc<+>,Atg7<tm1Tchi>/Atg7<tm1Tchi>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atg7<tm1Tchi>|Tg(Vil-cre/ERT2)23Syr|Apc<tm2.1Cip>|Apc<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased interleukin-1 beta secretion
  http://purl.obolibrary.org/obo/MP_0008657

文献

http://purl.org/net/cito/citesAsAuthority

• Jonathan. Lévy, et.al., Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth., Nature cell biology, 2015, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/26214133