increased interleukin-17 secretion_Nlrp3<tm1Wstr>/Nlrp3<+>

http://metadb.riken.jp/0008681IC57BL6Nlrp3tm1WstrNlrp3Nlrp3Nlrp3tm1Wstr

increased interleukin-17 secretion_Nlrp3<tm1Wstr>/Nlrp3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NLR family, pyrin domain containing 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2653833

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nlrp3<tm1Wstr>/Nlrp3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nlrp3<+>|Nlrp3<tm1Wstr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased interleukin-17 secretion
  http://purl.obolibrary.org/obo/MP_0008681

文献

http://purl.org/net/cito/citesAsAuthority

• Guangxun. Meng, et.al., A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19501001