increased interleukin-2 secretion_Gna12<tm1Citb>/Gna12<tm1Citb>,Gna13<tm2.1Soff>/Gna13<tm2.1Soff>,Tg(Lck-cre)548Jxm/0

http://metadb.riken.jp/0008687I129S1SvC57BL6CBAGna12tm1CitbGna12tm1CitbGna13tm21SoffGna13tm21SoffTgLckcre548Jxm0Gna12tm1CitbGna13tm21SoffTgLckcre548Jxm

increased interleukin-2 secretion_Gna12<tm1Citb>/Gna12<tm1Citb>,Gna13<tm2.1Soff>/Gna13<tm2.1Soff>,Tg(Lck-cre)548Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• guanine nucleotide binding protein, alpha 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:95767
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198
• guanine nucleotide binding protein, alpha 13
  http://metadb.riken.jp/db/mgi_rdf/MGI:95768

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gna12<tm1Citb>/Gna12<tm1Citb>,Gna13<tm2.1Soff>/Gna13<tm2.1Soff>,Tg(Lck-cre)548Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gna12<tm1Citb>|Gna13<tm2.1Soff>|Tg(Lck-cre)548Jxm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased interleukin-2 secretion
  http://purl.obolibrary.org/obo/MP_0008687

文献

http://purl.org/net/cito/citesAsAuthority

• Susanne. Herroeder, et.al., Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19409815