decreased interleukin-2 secretion_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>

http://metadb.riken.jp/0008688I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg

decreased interleukin-2 secretion_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neural precursor cell expressed, developmentally down-regulated 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:97297

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nedd4<Gt(XA209)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-2 secretion
  http://purl.obolibrary.org/obo/MP_0008688

文献

http://purl.org/net/cito/citesAsAuthority

• Baoli. Yang, et.al., Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18931680