Baoli. Yang, et.al., Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells., Nature immunology, 2008, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/18931680

Baoli. Yang, et.al., Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells., Nature immunology, 2008, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829272
• Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829273

class

http://purl.org/net/cito/citesAsAuthority

• Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829272
• Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829273

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal T cell activation_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0001828I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• increased IgM level_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0002494I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• increased IgM level_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0002494I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• increased T cell number_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0005015I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• increased T cell number_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0005015I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• decreased B cell number_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0005017I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
他17件を見る
• decreased B cell number_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0005017I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• decreased T cell proliferation_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0005095I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• decreased T cell proliferation_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0005095I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• increased CD4-positive, alpha beta T cell number_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0008074I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• increased CD4-positive, alpha beta T cell number_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0008074I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• increased CD8-positive, alpha-beta T cell number_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0008078I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• increased CD8-positive, alpha-beta T cell number_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0008078I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• decreased IgG1 level_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0008495I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• decreased IgG1 level_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0008495I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• decreased IgG2b level_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0008497I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• decreased IgG2b level_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0008497I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• decreased IgG3 level_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0008498I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• decreased IgG3 level_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0008498I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• decreased interleukin-2 secretion_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0008688I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• decreased interleukin-2 secretion_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0008688I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg
• perinatal lethality, complete penetrance_Nedd4<Gt(XA209)Byg>/Nedd4<Gt(XA209)Byg>
  http://metadb.riken.jp/0011089I129P2OlaHsdNedd4GtXA209BygNedd4GtXA209BygNedd4GtXA209Byg
• perinatal lethality, complete penetrance_Nedd4<Gt(XB398)Byg>/Nedd4<Gt(XB398)Byg>
  http://metadb.riken.jp/0011089I129P2OlaHsdNedd4GtXB398BygNedd4GtXB398BygNedd4GtXB398Byg