decreased susceptibility to endotoxin shock_Tnf<tm1.1Sned>/Tnf<tm1.1Sned>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008734I129C57BL6DBA2Tnftm11SnedTnftm11SnedTgCd4cre1Cwi0TgCd4cre1CwiTnftm11Sned

decreased susceptibility to endotoxin shock_Tnf<tm1.1Sned>/Tnf<tm1.1Sned>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• tumor necrosis factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104798

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tnf<tm1.1Sned>/Tnf<tm1.1Sned>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Tnf<tm1.1Sned>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008734

文献

http://purl.org/net/cito/citesAsAuthority

• Sergei I. Grivennikov, et.al., Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects., Immunity, 2005, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/15664162