abnormal B cell anergy_Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0

http://metadb.riken.jp/0008744IC57BL6TgIghelMD44Ccg0TgML5sHEL5Ccg0TgIghelMD44CcgTgML5sHEL5Ccg

abnormal B cell anergy_Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 4, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053738
• transgene insertion 5, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053866

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(IghelMD4)4Ccg|Tg(ML5sHEL)5Ccg

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal B cell anergy
  http://purl.obolibrary.org/obo/MP_0008744

文献

http://purl.org/net/cito/citesAsAuthority

• W Y. Ho, et.al., Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells., The Journal of experimental medicine, 1994, 179
  http://rdf.ncbi.nlm.nih.gov/pubmed/7909325
• Tri Giang. Phan, et.al., B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells., The Journal of experimental medicine, 2003, 197
  http://rdf.ncbi.nlm.nih.gov/pubmed/12668643