abnormal immunoglobulin heavy chain V(D)J recombination_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0

http://metadb.riken.jp/0008760I129P2OlaHsdC57BL6JIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvTgIGHyH2J92Jkbv0TgIGKyK2J231Jkbv0Igkctm1JkbvIghJtm1JkbvTgIGKyK2J231JkbvTgIGHyH2J92Jkbv

abnormal immunoglobulin heavy chain V(D)J recombination_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96461
• transgene insertion J9.2, Aya Jakobovits
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802719
• immunoglobulin kappa constant
  http://metadb.riken.jp/db/mgi_rdf/MGI:96495
• transgene insertion J23.1, Aya Jakobovits
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802720

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igkc<tm1Jkbv>|Igh-J<tm1Jkbv>|Tg(IGK@yK2)J23.1Jkbv|Tg(IGH@yH2)J9.2Jkbv

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal immunoglobulin heavy chain V(D)J recombination
  http://purl.obolibrary.org/obo/MP_0008760

文献

http://purl.org/net/cito/citesAsAuthority

• M J. Mendez, et.al., Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice., Nature genetics, 1997, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/9020839