increased B cell apoptosis_Prps2<tm1a(KOMP)Wtsi>/Y,Tg(IghMyc)22Bri/0

http://metadb.riken.jp/0008782IC57BL6NSJLPrps2tm1aKOMPWtsiYTgIghMyc22Bri0Prps2tm1aKOMPWtsiTgIghMyc22Bri

increased B cell apoptosis_Prps2<tm1a(KOMP)Wtsi>/Y,Tg(IghMyc)22Bri/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 22, Ralph L Brinster
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448238
• phosphoribosyl pyrophosphate synthetase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97776

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prps2<tm1a(KOMP)Wtsi>/Y,Tg(IghMyc)22Bri/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prps2<tm1a(KOMP)Wtsi>|Tg(IghMyc)22Bri

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell apoptosis
  http://purl.obolibrary.org/obo/MP_0008782

文献

http://purl.org/net/cito/citesAsAuthority

• John T. Cunningham, et.al., Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer., Cell, 2014, 157
  http://rdf.ncbi.nlm.nih.gov/pubmed/24855946