decreased B cell apoptosis_Gna12<tm1.1Cgh>/Gna12<tm1.1Cgh>,Gna13<tm2Cgh>/Gna13<tm2Cgh>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008783I129S4SvJaeC57BL6CBAGna12tm11CghGna12tm11CghGna13tm2CghGna13tm2CghTgMx1cre1Cgn0Gna13tm2CghGna12tm11CghTgMx1cre1Cgn

decreased B cell apoptosis_Gna12<tm1.1Cgh>/Gna12<tm1.1Cgh>,Gna13<tm2Cgh>/Gna13<tm2Cgh>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• guanine nucleotide binding protein, alpha 13
  http://metadb.riken.jp/db/mgi_rdf/MGI:95768
• guanine nucleotide binding protein, alpha 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:95767
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gna12<tm1.1Cgh>/Gna12<tm1.1Cgh>,Gna13<tm2Cgh>/Gna13<tm2Cgh>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gna13<tm2Cgh>|Gna12<tm1.1Cgh>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell apoptosis
  http://purl.obolibrary.org/obo/MP_0008783

文献

http://purl.org/net/cito/citesAsAuthority

• Jesse A. Green, et.al., The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement., Nature immunology, 2011, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/21642988