Jesse A. Green, et.al., The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement., Nature immunology, 2011, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/21642988

Jesse A. Green, et.al., The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement., Nature immunology, 2011, 12

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gna12<tm1.1Cgh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5140818

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased germinal center B cell number_Arhgef1<tm1Djle>/Arhgef1<tm1Djle>
  http://metadb.riken.jp/0008177I129S4SvJaeArhgef1tm1DjleArhgef1tm1DjleArhgef1tm1Djle
• decreased B cell apoptosis_Gna12<tm1.1Cgh>/Gna12<tm1.1Cgh>,Gna13<tm2Cgh>/Gna13<tm2Cgh>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008783I129S4SvJaeC57BL6CBAGna12tm11CghGna12tm11CghGna13tm2CghGna13tm2CghTgMx1cre1Cgn0Gna13tm2CghGna12tm11CghTgMx1cre1Cgn
• increased germinal center B cell number_S1pr2<tm1Rlp>/S1pr2<tm1Rlp>
  http://metadb.riken.jp/0008177I129S6SvEvTacC57BL6S1pr2tm1RlpS1pr2tm1RlpS1pr2tm1Rlp
• increased B cell number_S1pr2<tm1Rlp>/S1pr2<tm1Rlp>
  http://metadb.riken.jp/0005014I129S6SvEvTacC57BL6S1pr2tm1RlpS1pr2tm1RlpS1pr2tm1Rlp
• increased B cell proliferation_S1pr2<tm1Rlp>/S1pr2<tm1Rlp>
  http://metadb.riken.jp/0005154I129S6SvEvTacC57BL6S1pr2tm1RlpS1pr2tm1RlpS1pr2tm1Rlp
• increased germinal center B cell number_Gna12<tm1.1Cgh>/Gna12<tm1.1Cgh>,Gna13<tm2Cgh>/Gna13<tm2Cgh>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008177I129S4SvJaeC57BL6CBAGna12tm11CghGna12tm11CghGna13tm2CghGna13tm2CghTgMx1cre1Cgn0Gna13tm2CghGna12tm11CghTgMx1cre1Cgn
• increased T cell number_S1pr2<tm1Rlp>/S1pr2<tm1Rlp>
  http://metadb.riken.jp/0005015I129S6SvEvTacC57BL6S1pr2tm1RlpS1pr2tm1RlpS1pr2tm1Rlp
• decreased B cell apoptosis_S1pr2<tm1Rlp>/S1pr2<tm1Rlp>
  http://metadb.riken.jp/0008783I129S6SvEvTacC57BL6S1pr2tm1RlpS1pr2tm1RlpS1pr2tm1Rlp
• abnormal germinal center B cell morphology_Gna12<tm1.1Cgh>/Gna12<tm1.1Cgh>,Gna13<tm2Cgh>/Gna13<tm2Cgh>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008176I129S4SvJaeC57BL6CBAGna12tm11CghGna12tm11CghGna13tm2CghGna13tm2CghTgMx1cre1Cgn0Gna13tm2CghGna12tm11CghTgMx1cre1Cgn
• abnormal spleen germinal center morphology_S1pr2<tm1Rlp>/S1pr2<tm1Rlp>
  http://metadb.riken.jp/0002359I129S6SvEvTacC57BL6S1pr2tm1RlpS1pr2tm1RlpS1pr2tm1Rlp

class

http://purl.org/net/cito/citesAsAuthority

• Gna12<tm1.1Cgh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5140818