abnormal olfactory epithelium morphology_Gli3<tm1Alj>/Gli3<+>,Tgif1<tm1Caw>/Tgif1<tm1Caw>,Tgif2<tm1Dwot>/Tgif2<tm1Dwot>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0008789I129S6SvEvTac129X1SvJC57BL6JCBAGli3tm1AljGli3Tgif1tm1CawTgif1tm1CawTgif2tm1DwotTgif2tm1DwotTgSox2cre1Amc0Tgif1tm1CawGli3Tgif2tm1DwotGli3tm1AljTgSox2cre1Amc

abnormal olfactory epithelium morphology_Gli3<tm1Alj>/Gli3<+>,Tgif1<tm1Caw>/Tgif1<tm1Caw>,Tgif2<tm1Dwot>/Tgif2<tm1Dwot>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537
• TGFB-induced factor homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915299
• GLI-Kruppel family member GLI3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95729
• TGFB-induced factor homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1194497

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gli3<tm1Alj>/Gli3<+>,Tgif1<tm1Caw>/Tgif1<tm1Caw>,Tgif2<tm1Dwot>/Tgif2<tm1Dwot>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgif1<tm1Caw>|Gli3<+>|Tgif2<tm1Dwot>|Gli3<tm1Alj>|Tg(Sox2-cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal olfactory epithelium morphology
  http://purl.obolibrary.org/obo/MP_0008789

文献

http://purl.org/net/cito/citesAsAuthority

• Kenichiro. Taniguchi, et.al., Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway., PLoS genetics, 2012, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/22383895