increased circulating iron level_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<+>,Hfe<tm2Nca>/Hfe<tm2Nca>

http://metadb.riken.jp/0008810I129S4SvJae129S6SvEvTacFVBNGtROSA26Sortm1TfrcNcaGtROSA26SorHfetm2NcaHfetm2NcaGtROSA26Sortm1TfrcNcaHfetm2NcaGtROSA26Sor

increased circulating iron level_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<+>,Hfe<tm2Nca>/Hfe<tm2Nca>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hemochromatosis
  http://metadb.riken.jp/db/mgi_rdf/MGI:109191
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<+>,Hfe<tm2Nca>/Hfe<tm2Nca>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(Tfrc*)Nca>|Hfe<tm2Nca>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating iron level
  http://purl.obolibrary.org/obo/MP_0008810

文献

http://purl.org/net/cito/citesAsAuthority

• Paul J. Schmidt, et.al., The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression., Cell metabolism, 2008, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/18316026