Paul J. Schmidt, et.al., The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression., Cell metabolism, 2008, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/18316026

Paul J. Schmidt, et.al., The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression., Cell metabolism, 2008, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Ttr-Hfe)1Nca
  http://metadb.riken.jp/db/mgi_rdf/MGI:3778909
• Gt(ROSA)26Sor<tm1(Tfrc*)Nca>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3778905
• Tfrc<tm2Nca>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3778906

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating iron level_Hfe<tm2Nca>/Hfe<tm2Nca>,Tg(Ttr-Hfe)1Nca/0
  http://metadb.riken.jp/0004151I129S6SvEvTacC57BL6Hfetm2NcaHfetm2NcaTgTtrHfe1Nca0Hfetm2NcaTgTtrHfe1Nca
• increased circulating iron level_Hfe<tm2Nca>/Hfe<tm2Nca>
  http://metadb.riken.jp/0008810I129S6SvEvTacHfetm2NcaHfetm2NcaHfetm2Nca
• increased liver iron level_Hfe<tm2Nca>/Hfe<tm2Nca>
  http://metadb.riken.jp/0008807I129S6SvEvTacHfetm2NcaHfetm2NcaHfetm2Nca
• decreased circulating iron level_Tfrc<tm2Nca>/Tfrc<tm2Nca>
  http://metadb.riken.jp/0004151I129S4SvJaeFVBNTfrctm2NcaTfrctm2NcaTfrctm2Nca
• increased liver iron level_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<tm1(Tfrc*)Nca>
  http://metadb.riken.jp/0008807I129S4SvJaeFVBNGtROSA26Sortm1TfrcNcaGtROSA26Sortm1TfrcNcaGtROSA26Sortm1TfrcNca
• increased heart iron level_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<tm1(Tfrc*)Nca>
  http://metadb.riken.jp/0020367I129S4SvJaeFVBNGtROSA26Sortm1TfrcNcaGtROSA26Sortm1TfrcNcaGtROSA26Sortm1TfrcNca
• increased liver iron level_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<+>,Hfe<tm2Nca>/Hfe<tm2Nca>
  http://metadb.riken.jp/0008807I129S4SvJae129S6SvEvTacFVBNGtROSA26Sortm1TfrcNcaGtROSA26SorHfetm2NcaHfetm2NcaGtROSA26Sortm1TfrcNcaHfetm2NcaGtROSA26Sor
• hypochromic microcytic anemia_Hfe<tm2Nca>/Hfe<tm2Nca>,Tg(Ttr-Hfe)1Nca/0
  http://metadb.riken.jp/0008388I129S6SvEvTacC57BL6Hfetm2NcaHfetm2NcaTgTtrHfe1Nca0Hfetm2NcaTgTtrHfe1Nca
• increased circulating iron level_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<tm1(Tfrc*)Nca>
  http://metadb.riken.jp/0008810I129S4SvJaeFVBNGtROSA26Sortm1TfrcNcaGtROSA26Sortm1TfrcNcaGtROSA26Sortm1TfrcNca
• hypochromic microcytic anemia_Tfrc<tm2Nca>/Tfrc<tm2Nca>
  http://metadb.riken.jp/0008388I129S4SvJaeFVBNTfrctm2NcaTfrctm2NcaTfrctm2Nca
• decreased liver iron level_Hfe<tm2Nca>/Hfe<tm2Nca>,Tg(Ttr-Hfe)1Nca/0
  http://metadb.riken.jp/0008743I129S6SvEvTacC57BL6Hfetm2NcaHfetm2NcaTgTtrHfe1Nca0Hfetm2NcaTgTtrHfe1Nca
• increased circulating iron level_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<+>,Hfe<tm2Nca>/Hfe<tm2Nca>
  http://metadb.riken.jp/0008810I129S4SvJae129S6SvEvTacFVBNGtROSA26Sortm1TfrcNcaGtROSA26SorHfetm2NcaHfetm2NcaGtROSA26Sortm1TfrcNcaHfetm2NcaGtROSA26Sor

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Ttr-Hfe)1Nca
  http://metadb.riken.jp/db/mgi_rdf/MGI:3778909
• Gt(ROSA)26Sor<tm1(Tfrc*)Nca>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3778905
• Tfrc<tm2Nca>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3778906