decreased common myeloid progenitor cell number_Ptpn11<tm6Bgn>/Ptpn11<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008813I129S6SvEvTacC57BL6CBAPtpn11tm6BgnPtpn11TgMx1cre1Cgn0Ptpn11Ptpn11tm6BgnTgMx1cre1Cgn

decreased common myeloid progenitor cell number_Ptpn11<tm6Bgn>/Ptpn11<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• protein tyrosine phosphatase, non-receptor type 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:99511

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptpn11<tm6Bgn>/Ptpn11<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptpn11<+>|Ptpn11<tm6Bgn>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased common myeloid progenitor cell number
  http://purl.obolibrary.org/obo/MP_0008813

文献

http://purl.org/net/cito/citesAsAuthority

• Gordon. Chan, et.al., Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis., Blood, 2009, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/19179468