decreased nerve conduction velocity_Egr2<tm2(cre)Pch>/Egr2<+>,Ptpn11<tm1.1Wbm>/Ptpn11<tm1.1Wbm>

http://metadb.riken.jp/0008814I129P2OlaHsd129S2SvPasC57BL6SJLEgr2tm2crePchEgr2Ptpn11tm11WbmPtpn11tm11WbmPtpn11tm11WbmEgr2tm2crePchEgr2

decreased nerve conduction velocity_Egr2<tm2(cre)Pch>/Egr2<+>,Ptpn11<tm1.1Wbm>/Ptpn11<tm1.1Wbm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• early growth response 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95296
• protein tyrosine phosphatase, non-receptor type 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:99511

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Egr2<tm2(cre)Pch>/Egr2<+>,Ptpn11<tm1.1Wbm>/Ptpn11<tm1.1Wbm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptpn11<tm1.1Wbm>|Egr2<tm2(cre)Pch>|Egr2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased nerve conduction velocity
  http://purl.obolibrary.org/obo/MP_0008814

文献

http://purl.org/net/cito/citesAsAuthority

• Katja S. Grossmann, et.al., The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19805360