abnormal splenic cell ratio_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0

http://metadb.riken.jp/0008826I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs

abnormal splenic cell ratio_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1a, Jeffrey Bluestone
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430212
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dicer1<tm1Bdh>|Tg(Foxp3-EGFP/icre)1aJbs

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * NOD/ShiLt

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal splenic cell ratio
  http://purl.obolibrary.org/obo/MP_0008826

文献

http://purl.org/net/cito/citesAsAuthority

• Xuyu. Zhou, et.al., Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity., The Journal of experimental medicine, 2008, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/18725525