Xuyu. Zhou, et.al., Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity., The Journal of experimental medicine, 2008, 205

http://rdf.ncbi.nlm.nih.gov/pubmed/18725525

Xuyu. Zhou, et.al., Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity., The Journal of experimental medicine, 2008, 205

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Foxp3-EGFP/icre)1aJbs
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430213

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Foxp3-EGFP/icre)1aJbs
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430213

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged lymph nodes_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0000702I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• abnormal effector T cell morphology_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0002435I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• abnormal regulatory T cell morphology_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0004941I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• abnormal CD4-positive, alpha-beta T cell physiology_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0005463I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• decreased regulatory T cell number_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0004974I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• enlarged spleen_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0000691I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• abnormal behavior_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0004924I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• lung inflammation_Foxp3<sf>/?
  http://metadb.riken.jp/0001861NSFoxp3sfFoxp3sf
• weight loss_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0001263I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• liver inflammation_Foxp3<sf>/?
  http://metadb.riken.jp/0001860NSFoxp3sfFoxp3sf
• abnormal regulatory T cell physiology_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0004946I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• kyphosis_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0000160I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• lung inflammation_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0001861I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• abnormal splenic cell ratio_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0008826I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• premature death_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0002083I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• abnormal lymph node cell ratio_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0008828I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs
• liver inflammation_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Tg(Foxp3-EGFP/icre)1aJbs/0
  http://metadb.riken.jp/0001860I129NODShiLtDicer1tm1BdhDicer1tm1BdhTgFoxp3EGFPicre1aJbs0Dicer1tm1BdhTgFoxp3EGFPicre1aJbs