chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>

http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm4GtRRE056BygMcm4Mcm4GtRRE056BygMcm2GtAB0178WtsiMcm4Mcm2

chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• minichromosome maintenance complex component 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:103199
• minichromosome maintenance complex component 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:105380

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mcm4<Gt(RRE056)Byg>|Mcm2<Gt(AB0178)Wtsi>|Mcm4<+>|Mcm2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C3HeB/FeJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• chromosomal instability
  http://purl.obolibrary.org/obo/MP_0008866

文献

http://purl.org/net/cito/citesAsAuthority

• Chen-Hua. Chuang, et.al., Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress., PLoS genetics, 2010, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/20838603