chromosomal instability_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>

http://metadb.riken.jp/0008866I129P2OlaHsdC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiTrp53tm1MlhTrp53tm1MlhRnaseh2btm1aEUCOMMWtsiTrp53tm1Mlh

chromosomal instability_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• ribonuclease H2, subunit B
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914403

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rnaseh2b<tm1a(EUCOMM)Wtsi>|Trp53<tm1Mlh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• chromosomal instability
  http://purl.obolibrary.org/obo/MP_0008866

文献

http://purl.org/net/cito/citesAsAuthority

• Martin A M. Reijns, et.al., Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development., Cell, 2012, 149
  http://rdf.ncbi.nlm.nih.gov/pubmed/22579044