http://rdf.ncbi.nlm.nih.gov/pubmed/22579044

http://rdf.ncbi.nlm.nih.gov/pubmed/22579044

Martin A M. Reijns, et.al., Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development., Cell, 2012, 149

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431529

class

http://purl.org/net/cito/citesAsAuthority

• Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431529

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic growth retardation_Rnaseh2b<tm1Hgu>/Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/0003984I129P2OlaHsdC57BL6JRnaseh2btm1HguRnaseh2btm1HguRnaseh2btm1Hgu
• decreased embryo size_Rnaseh2b<tm1Hgu>/Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/0001698I129P2OlaHsdC57BL6JRnaseh2btm1HguRnaseh2btm1HguRnaseh2btm1Hgu
• abnormal cell morphology_Rnaseh2b<tm1Hgu>/Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/0000358I129P2OlaHsdC57BL6JRnaseh2btm1HguRnaseh2btm1HguRnaseh2btm1Hgu
• preweaning lethality_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0010770IC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsi
• decreased embryo size_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001698IC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsi
• abnormal allantois morphology_Rnaseh2b<tm1Hgu>/Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/0001726I129P2OlaHsdC57BL6JRnaseh2btm1HguRnaseh2btm1HguRnaseh2btm1Hgu
• embryonic growth retardation_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003984IC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsi
• increased cellular sensitivity to alkylating agents_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>
  http://metadb.riken.jp/0008402I129P2OlaHsdC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiTrp53tm1MlhTrp53tm1MlhRnaseh2btm1aEUCOMMWtsiTrp53tm1Mlh
• embryonic growth retardation_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>
  http://metadb.riken.jp/0003984I129P2OlaHsdC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiTrp53tm1MlhTrp53tm1MlhRnaseh2btm1aEUCOMMWtsiTrp53tm1Mlh
• abnormal cell nucleus morphology_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>
  http://metadb.riken.jp/0003111I129P2OlaHsdC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiTrp53tm1MlhTrp53tm1MlhRnaseh2btm1aEUCOMMWtsiTrp53tm1Mlh
• preweaning lethality_Rnaseh2b<tm1Hgu>/Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/0010770I129P2OlaHsdC57BL6JRnaseh2btm1HguRnaseh2btm1HguRnaseh2btm1Hgu
• abnormal neural tube closure_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>
  http://metadb.riken.jp/0003720I129P2OlaHsdC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiTrp53tm1MlhTrp53tm1MlhRnaseh2btm1aEUCOMMWtsiTrp53tm1Mlh
• caudal body truncation_Rnaseh2b<tm1Hgu>/Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/0004073I129P2OlaHsdC57BL6JRnaseh2btm1HguRnaseh2btm1HguRnaseh2btm1Hgu
• chromosomal instability_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>
  http://metadb.riken.jp/0008866I129P2OlaHsdC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiTrp53tm1MlhTrp53tm1MlhRnaseh2btm1aEUCOMMWtsiTrp53tm1Mlh
• decreased cell proliferation_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000352IC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsi
• decreased embryo size_Rnaseh2b<tm1a(EUCOMM)Wtsi>/Rnaseh2b<tm1a(EUCOMM)Wtsi>,Trp53<tm1Mlh>/Trp53<tm1Mlh>
  http://metadb.riken.jp/0001698I129P2OlaHsdC57BL6NRnaseh2btm1aEUCOMMWtsiRnaseh2btm1aEUCOMMWtsiTrp53tm1MlhTrp53tm1MlhRnaseh2btm1aEUCOMMWtsiTrp53tm1Mlh
• impaired somite development_Rnaseh2b<tm1Hgu>/Rnaseh2b<tm1Hgu>
  http://metadb.riken.jp/0009768I129P2OlaHsdC57BL6JRnaseh2btm1HguRnaseh2btm1HguRnaseh2btm1Hgu