increased physiological sensitivity to xenobiotic_Cyp1a1<tm4.1Dwn>/Cyp1a1<tm4.1Dwn>

http://metadb.riken.jp/0008873B6129X1Cyp1a1tm41DwnCyp1a1tm41DwnCyp1a1tm41DwnCyp1a1tm41Dwn

increased physiological sensitivity to xenobiotic_Cyp1a1<tm4.1Dwn>/Cyp1a1<tm4.1Dwn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytochrome P450, family 1, subfamily a, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88588

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cyp1a1<tm4.1Dwn>/Cyp1a1<tm4.1Dwn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cyp1a1<tm4.1Dwn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129X1-Cyp1a1<tm4.1Dwn>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• Hongbin. Dong, et.al., Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle., Molecular pharmacology, 2009, 75
  http://rdf.ncbi.nlm.nih.gov/pubmed/19047483