increased physiological sensitivity to xenobiotic_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>

http://metadb.riken.jp/0008873I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy

increased physiological sensitivity to xenobiotic_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tyrosyl-DNA phosphodiesterase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1860486

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tdp2<tm1.1Huy>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• Fernando. Gómez-Herreros, et.al., TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo., PLoS genetics, 2013, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/23505375