Fernando. Gómez-Herreros, et.al., TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo., PLoS genetics, 2013, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/23505375

Fernando. Gómez-Herreros, et.al., TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo., PLoS genetics, 2013, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tdp2<tm1.1Huy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5503302
• Tdp2<tm1Huy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5503301

class

http://purl.org/net/cito/citesAsAuthority

• Tdp2<tm1.1Huy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5503302
• Tdp2<tm1Huy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5503301

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thymus atrophy_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0003644I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• abnormal cell nucleus morphology_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0003111I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• abnormal erythroblast morphology_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0011176I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• small intestinal villus atrophy_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0014078I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• increased susceptibility to weight loss_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0010180I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• abnormal mitosis_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0004046I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• increased physiological sensitivity to xenobiotic_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0008873I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• abnormal chromosome morphology_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0003702I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• abnormal immature B cell morphology_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0005022I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• no abnormal phenotype detected_Tdp2<tm1Huy>/Tdp2<tm1Huy>
  http://metadb.riken.jp/0002169I129P2OlaHsdCD1Tdp2tm1HuyTdp2tm1HuyTdp2tm1Huy
• decreased double-positive T cell number_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0005092I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• abnormal immune system organ morphology_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0002722I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• spleen atrophy_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0003643I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy
• abnormal lymphopoiesis_Tdp2<tm1.1Huy>/Tdp2<tm1.1Huy>
  http://metadb.riken.jp/0002401I129P2OlaHsdCD1Tdp2tm11HuyTdp2tm11HuyTdp2tm11Huy