increased physiological sensitivity to xenobiotic_Fan1<tm1d(KOMP)Wtsi>/Fan1<tm1d(KOMP)Wtsi>,Fancd2<tm1Hou>/Fancd2<tm1Hou>

http://metadb.riken.jp/0008873I129S4SvJaeC57BL6NFVBNFan1tm1dKOMPWtsiFan1tm1dKOMPWtsiFancd2tm1HouFancd2tm1HouFan1tm1dKOMPWtsiFancd2tm1Hou

increased physiological sensitivity to xenobiotic_Fan1<tm1d(KOMP)Wtsi>/Fan1<tm1d(KOMP)Wtsi>,Fancd2<tm1Hou>/Fancd2<tm1Hou>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• FANCD2/FANCI-associated nuclease 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:3045266
• Fanconi anemia, complementation group D2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448480

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fan1<tm1d(KOMP)Wtsi>/Fan1<tm1d(KOMP)Wtsi>,Fancd2<tm1Hou>/Fancd2<tm1Hou>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fan1<tm1d(KOMP)Wtsi>|Fancd2<tm1Hou>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6N * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• Supawat. Thongthip, et.al., Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction., Genes & development, 2016, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/26980189