increased physiological sensitivity to xenobiotic_Mt1<tm1Bri>/Mt1<tm1Bri>,Mt2<tm1Bri>/Mt2<tm1Bri>

http://metadb.riken.jp/0008873I129S7SvEvBrdMt1tm1BriMt1tm1BriMt2tm1BriMt2tm1BriMt1tm1BriMt2tm1Bri

increased physiological sensitivity to xenobiotic_Mt1<tm1Bri>/Mt1<tm1Bri>,Mt2<tm1Bri>/Mt2<tm1Bri>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• metallothionein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97171
• metallothionein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mt1<tm1Bri>/Mt1<tm1Bri>,Mt2<tm1Bri>/Mt2<tm1Bri>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mt1<tm1Bri>|Mt2<tm1Bri>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• J. Liu, et.al., Metallothionein-I/II knockout mice are sensitive to acetaminophen-induced hepatotoxicity., The Journal of pharmacology and experimental therapeutics, 1999, 289
  http://rdf.ncbi.nlm.nih.gov/pubmed/10087053