decreased neuron number_Tg(CAG-Ppard*E411P)#Als/0,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0008948B6JCgTgNescre1KlnTgCAGPpardE411PAlsTgCAGPpardE411PAls0TgNescre1Kln0TgCAGPpardE411PAlsTgNescre1Kln

decreased neuron number_Tg(CAG-Ppard*E411P)#Als/0,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Albert R La Spada
  http://metadb.riken.jp/db/mgi_rdf/MGI:5897171
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(CAG-Ppard*E411P)#Als/0,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-Ppard*E411P)#Als|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6J.Cg-Tg(Nes-cre)1Kln Tg(CAG-Ppard*E411P)#Als

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased neuron number
  http://purl.obolibrary.org/obo/MP_0008948

文献

http://purl.org/net/cito/citesAsAuthority

• Audrey S. Dickey, et.al., PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically., Nature medicine, 2016, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/26642438