increased pancreatic beta cell mass_Cebpb<tm1.1Maka>/Cebpb<tm1.1Maka>,Lepr<db>/Lepr<db>,Tg(Ins2-cre)23Herr/0

http://metadb.riken.jp/0009113I129P2OlaHsdC57BL6JC57BLKSJCBAJCebpbtm11MakaCebpbtm11MakaLeprdbLeprdbTgIns2cre23Herr0Cebpbtm11MakaTgIns2cre23HerrLeprdb

increased pancreatic beta cell mass_Cebpb<tm1.1Maka>/Cebpb<tm1.1Maka>,Lepr<db>/Lepr<db>,Tg(Ins2-cre)23Herr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CCAAT/enhancer binding protein (C/EBP), beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:88373
• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993
• transgene insertion 23, Pedro Luis Herrera
  http://metadb.riken.jp/db/mgi_rdf/MGI:4431238

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cebpb<tm1.1Maka>/Cebpb<tm1.1Maka>,Lepr<db>/Lepr<db>,Tg(Ins2-cre)23Herr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cebpb<tm1.1Maka>|Tg(Ins2-cre)23Herr|Lepr<db>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * C57BLKS/J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic beta cell mass
  http://purl.obolibrary.org/obo/MP_0009113

文献

http://purl.org/net/cito/citesAsAuthority

• Tomokazu. Matsuda, et.al., Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/19955657