increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0009151I129S4SvJaeBALBcC57BL6Krastm4TyjKrasPtentm1HwuPtenTgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamPtenPtentm1Hwu

increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<+>|Kras<tm4Tyj>|Tg(Pdx1-cre)89.1Dam|Pten<+>|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic ductal adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009151

文献

http://purl.org/net/cito/citesAsAuthority

• Reginald. Hill, et.al., PTEN loss accelerates KrasG12D-induced pancreatic cancer development., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/20807812