Reginald. Hill, et.al., PTEN loss accelerates KrasG12D-induced pancreatic cancer development., Cancer research, 2010, 70

http://rdf.ncbi.nlm.nih.gov/pubmed/20807812

Reginald. Hill, et.al., PTEN loss accelerates KrasG12D-induced pancreatic cancer development., Cancer research, 2010, 70

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009152I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasPtentm1HwuPtentm1HwuTgPdx1cre891Dam0KrasTgPdx1cre891DamKrastm4TyjPtentm1Hwu
• ascites_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005324I129S4SvJaeC57BL6CBAKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKras
• edema_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001785I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasPtentm1HwuPtentm1HwuTgPdx1cre891Dam0KrasTgPdx1cre891DamKrastm4TyjPtentm1Hwu
• increased pancreas tumor incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129S4SvJaeBALBcC57BL6Krastm4TyjKrasPtentm1HwuPtenTgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamPtenPtentm1Hwu
• increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009152I129S4SvJaeC57BL6CBAKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKras
• distended abdomen_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001270I129S4SvJaeC57BL6CBAKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKras
• abnormal exocrine pancreas morphology_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005220I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasPtentm1HwuPtentm1HwuTgPdx1cre891Dam0KrasTgPdx1cre891DamKrastm4TyjPtentm1Hwu
• premature death_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0002083I129S4SvJaeBALBcC57BL6Krastm4TyjKrasPtentm1HwuPtenTgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamPtenPtentm1Hwu
• exocrine pancreas atrophy_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009164I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasPtentm1HwuPtentm1HwuTgPdx1cre891Dam0KrasTgPdx1cre891DamKrastm4TyjPtentm1Hwu
• increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009152I129S4SvJaeBALBcC57BL6Krastm4TyjKrasPtentm1HwuPtenTgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamPtenPtentm1Hwu
• increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129S4SvJaeC57BL6CBAKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKras
• increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasPtentm1HwuPtentm1HwuTgPdx1cre891Dam0KrasTgPdx1cre891DamKrastm4TyjPtentm1Hwu
• pancreatic acinar-to-ductal metaplasia_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0013221I129S4SvJaeC57BL6CBAKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKras
• pancreatic acinar-to-ductal metaplasia_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0013221I129S4SvJaeBALBcC57BL6Krastm4TyjKrasPtentm1HwuPtenTgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamPtenPtentm1Hwu
• increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129S4SvJaeBALBcC57BL6Krastm4TyjKrasPtentm1HwuPtenTgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamPtenPtentm1Hwu
• pancreatic acinar-to-ductal metaplasia_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0013221I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasPtentm1HwuPtentm1HwuTgPdx1cre891Dam0KrasTgPdx1cre891DamKrastm4TyjPtentm1Hwu
• postnatal lethality, complete penetrance_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0011085I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasPtentm1HwuPtentm1HwuTgPdx1cre891Dam0KrasTgPdx1cre891DamKrastm4TyjPtentm1Hwu